Is ARCOXIA a COX-2 inhibitor?

Is ARCOXIA a COX-2 inhibitor?

What is ARCOXIA? ARCOXIA contains the active substance etoricoxib. ARCOXIA is one of a group of medicines called selective COX-2 inhibitors. These belong to a family of medicines called non-steroidal anti-inflammatory drugs (NSAIDs).

Is etoricoxib a COX-2?

Etoricoxib is a potent selective COX-2 inhibitor in man. Ex vivo whole-blood assays assessed COX-2 inhibition after oral administration of etoricoxib in single (5-500 mg) and multiple (25-150 mg) once-daily doses to healthy human subjects.

Why is Arcoxia banned in the US?

GAITHERSBURG, Md., April 12 — A panel of federal drug advisers voted 20 to 1 Thursday to reject an application by Merck to sell its pain pill Arcoxia because of concerns that the drug could cause as many as 30,000 heart attacks annually if widely used.

Is Arcoxia still banned in the US?

Note: Arcoxia has not been approved by the FDA for the U.S. market. Take Arcoxia only when prescribed by your doctor. For osteoarthritis, the recommended dose is 60 mg once a day. For rheumatoid arthritis the recommended dose is 90 mg once a day.

Why is COX-2 withdrawn?

Objective: Cyclo-oxygenase-2 (COX-2) inhibitors rofecoxib and valdecoxib were withdrawn from the market because of their association with cardiovascular problems. There is a lack of information on the impact of the COX-2 inhibitors withdrawal on the prescribing and utilization of related drugs.

Is ARCOXIA better than Celebrex?

Conclusions. Etoricoxib is more effective than celecoxib and placebo for using as preemptive analgesia for acute postoperative pain control in patients underwent arthroscopic anterior cruciate ligament reconstruction.

Is ARCOXIA and etoricoxib the same?

Arcoxia is a brand name for etoricoxib. Unbranded generic etoricoxib tablets are also available. There are four strengths of tablet available 30 mg, 60 mg, 90 mg and 120 mg. Arcoxia (etoricoxib) is only available on prescription.

How safe is Arcoxia?

Arcoxia can increase blood pressure in some people, especially in high doses, and this could increase the risk of heart attacks and strokes. Your doctor will want to check your blood pressure from time to time, to make sure that it is safe to continue treatment.

Is Arcoxia approved in USA?

Merck’s new pain reliever drug Arcoxia, which was proposed as a successor to Vioxx, was rejected by a federal health advisory panel. The news came out just after the market closed.

Why is Arcoxia not FDA approved?

What is an alternative to Arcoxia?

Celecoxib, Etoricoxib, and Diclofenac Have Comparable Efficacy in Patients With Arthritic Conditions.

How safe is ARCOXIA?

What can I take instead of ARCOXIA?

The main types of NSAIDs include:

• ibuprofen.
• naproxen.
• diclofenac.
• celecoxib.
• mefenamic acid.
• etoricoxib.
• indomethacin.
• high-dose aspirin (low-dose aspirin is not normally considered to be an NSAID)