What are leukotriene receptor antagonists used for?

What are leukotriene receptor antagonists used for?

Leukotriene modifiers, also called leukotriene receptor antagonists, are a group of medications. They can help prevent breathing problems associated with allergies, asthma and chronic obstructive pulmonary disease. Examples include montelukast, zafirlukast and zileuton.

What are the indications for montelukast?

montelukast (Rx)

• Asthma. Indicated for prophylaxis and chronic treatment of asthma.
• Exercise-Induced Bronchospasm. Indicated for prevention of exercise-induced bronchoconstriction (EIB)
• Allergic or Perennial Rhinitis. Indicated for symptomatic relief of seasonal or perennial allergic rhinitis.
• Dosage Modifications.

What is the indication for Singulair?

SINGULAIR® is indicated for the prophylaxis and chronic treatment of asthma in adults and pediatric patients 12 months of age and older. SINGULAIR is indicated for prevention of exercise-induced bronchoconstriction (EIB) in patients 6 years of age and older.

When should leukotriene inhibitors not be given?

Who should not use leukotriene modifiers for allergies? The safety and effectiveness of using leukotriene inhibitors for treatment of asthma in children under age 12 months or the treatment of perennial allergic rhinitis in infants under 6 months has not been established.

What is montelukast used for and side effects?

Montelukast is used to prevent wheezing, difficulty breathing, chest tightness, and coughing caused by asthma in adults and children 12 months of age and older. Montelukast is also used to prevent bronchospasm (breathing difficulties) during exercise in adults and children 6 years of age and older.

Which are leukotriene modifiers primarily used for?

Leukotriene Modifiers: Used to treat allergy symptoms and to prevent asthma symptoms.
Generic Name	Brand Name	Use
Zafirlukast	Accolate 10 or 20 mg Tablets	To prevent and treat asthma ages 5 and above.
Zileuton	Zyflo CR Tablets 600 mg Zyflo CR PDF	To prevent and treat asthma ages 12 and older.

Which condition is a contraindication for the administration of montelukast?

Montelukast is contraindicated in patients with a history of hypersensitivity to the drug or its components. In addition, for patients with phenylketonuria (PKU), caution should be exercised with phenylalanine-containing formulations.

What should you check before administering montelukast?

Before taking montelukast, Be sure to mention gemfibrozil (Lopid), phenobarbital and rifampin (Rifadin, Rimactane, in Rifamate, Rifater). Your doctor may need to change the doses of your medications or monitor you more carefully for side effects. tell your doctor if you have or have ever had liver disease.

What are the contraindications of Singulair?

The following conditions are contraindicated with this drug….Who should not take SINGULAIR?

• PKU – phenylketonuria.
• increased eosinophils in the blood.
• suicidal thoughts.
• depression.
• inflammation of blood vessels in the skin.
• anxiety disorder.

What are the side effects of leukotriene receptor antagonists?

Side effects of leukotriene receptor antagonists may include the following:

• Headache.
• Abdominal pain.
• Laryngitis (inflammation of the larynx)
• Pharyngitis (throat inflammation)
• Wheezing.
• Viral infection.
• Nausea.
• Vomiting.

Is montelukast a leukotriene receptor antagonist?

Montelukast is a potent, specific antagonist of leukotriene receptors10,11 that was recently approved in the United States and other countries for the treatment of chronic asthma. The protective effects of two doses of montelukast on exercise-induced bronchoconstriction have been shown at 20 to 24 hours after dosing.

What are the contraindications of montelukast?

Contraindications / Precautions

• General Information.
• Acute bronchospasm, status asthmaticus.
• Phenylketonuria.
• Behavioral changes, depression, neurologic events, psychiatric event, suicidal ideation.
• Pregnancy.
• Breast-feeding.
• Infants, neonates.
• Alcoholism, hepatic disease, hepatitis, jaundice.

Which drug is used as leukotriene antagonist?

Leukotriene Antagonists

Drug	Drug Description
Montelukast	A leukotriene receptor antagonist used as part of an asthma therapy regimen, to prevent exercise induced bronchoconstriction, and to treat seasonal allergic rhinitis.
Zafirlukast	A leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma.

Can you take montelukast with high blood pressure?

If you have high blood pressure or edema (excess fluid in your body), your doctor may have told you to limit your sodium intake. But taking montelukast oral tablets won’t affect these conditions. It shouldn’t increase your blood sodium levels, weight, or blood pressure.

What medications should not be given before dialysis?

Be Aware – Medications NOT to Take Before Dialysis

• Blood pressure medications.
• Antibiotic medications.

Can Singulair be taken with kidney?

No dosage adjustment is needed in people with kidney disease. Appears to have few significant drug interactions. Taken once a day. May be taken with or without food.

Does montelukast sodium raise blood pressure?

It shouldn’t. In clinical studies, montelukast oral tablets weren’t reported to cause weight gain or increased blood pressure. Steroid treatments for asthma, such as prednisone, may cause weight gain or increased blood pressure.

What medications are contraindicated with hemodialysis?

Unfractionated heparin is preferred for acute treatment of venous thromboembolism in patients on dialysis. The newer oral anticoagulants (such as dabigatran and rivaroxaban) are contraindicated. They all undergo a degree of renal clearance which makes them unsuitable for patients on dialysis.