How effective is cladribine for hairy cell leukemia?

How effective is cladribine for hairy cell leukemia?

Hairy cell leukemia (HCL) is an indolent B-cell neoplasm comprising 2% of leukemias, estimated at 1,100-1,240 new cases per year in the United States. Standard first-line purine analogs cladribine or pentostatin achieve 75%-90% complete remission (CR) rates.

What drugs are used to treat hairy cell leukemia?

Cladribine and pentostatin are anticancer drugs commonly used to treat hairy cell leukemia.

What are the 3 organs affected in hairy cell leukemia?

Hairy cell leukemia most commonly affects the bone marrow and spleen. However, because HCL travels between the bone marrow, spleen, liver and lymph nodes via the bloodstream, it may potentially affect any part of the body that the blood circulates to.

Does hairy cell leukemia always come back?

Treatment is very successful and usually puts the disease into remission (no evidence of hairy cell leukaemia on your tests). Remissions often last many years but hairy cell leukaemia usually comes back (relapses) and needs more treatment at some point.

Can you live a full life with hairy cell leukemia?

Generally for people with hairy cell leukaemia: around 95 out of every 100 (around 95%) will survive their leukaemia for 5 years or more after they are diagnosed.

What are the side effects of cladribine?

Cladribine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• nausea.
• vomiting.
• diarrhea.
• stomach pain.
• constipation.
• loss of appetite.
• skin rash.
• headache.

What is the best treatment for hairy cell leukemia?

Chemotherapy. Doctors consider chemotherapy drugs the first line of treatment for hairy cell leukemia. A great majority of people will experience complete or partial remission through the use of chemotherapy.

What is life expectancy for hairy cell leukemia?

What is the survival rate for hairy cell leukemia?

Survival statistics for hairy cell leukaemia Generally for people with hairy cell leukaemia: around 95 out of every 100 (around 95%) will survive their leukaemia for 5 years or more after they are diagnosed.

Is hairy cell leukemia curable?

There is no cure for hairy cell leukemia. But treatments are effective at putting hairy cell leukemia in remission for years.

Can you recover from hairy cell leukemia?

The majority of people with hairy cell leukemia eventually need treatment. There is no cure for hairy cell leukemia. But treatments are effective at putting hairy cell leukemia in remission for years.

How serious is hairy cell leukemia?

Untreated hairy cell leukemia that progresses may crowd out healthy blood cells in the bone marrow, leading to serious complications, such as: Infections. Reduced numbers of healthy white blood cells put you at risk of infections that your body might otherwise fight off. Bleeding.