What is tolvaptan tablets for?

What is tolvaptan tablets for?

Tolvaptan is used to treat hyponatremia (low sodium in the blood) in patients with heart failure or syndrome of inappropriate antidiuretic hormone (SIADH). Tolvaptan is also used to slow kidney function decline in adults who are at risk of rapidly progressing autosomal dominant polycystic kidney disease (ADPKD).

How effective is tolvaptan for PKD?

Tolvaptan slowed a loss of renal function bŷ25% compared to placebo, with a reduction in the rate of deterioration of 1.20 mg/mL/year (95% CI: 0.62–1.78; p<0.001).

Does tolvaptan shrink cysts?

Tolvaptan. Tolvaptan is a medication that’s recommended by the National Institute for Health and Care Excellence (NICE) to treat ADPKD in adults. It can be used to slow down the growth of cysts, reducing overall kidney growth and preserving kidney function for longer.

Is tolvaptan expensive?

At a drug cost of $5,760 per month, tolvaptan cost $744,100 per QALY gained compared to standard care.

Is tolvaptan available in India?

Tolvaptan 15mg Brands in India :

Product Company Price (Rs.)
Tvaptan 15 mg Tablet 10s Centaur Labs 395.41
Natrise 15mg Tablet 4s Sun Pharma 396.00
Tolvasca 15mg Tablet 4s Glenmark 524.50
Resodim 15 mg Tablet 4s Lupin 575.55

Is there a generic for tolvaptan?

May 20, 2020 – Alkem/Ascend and Apotex launched AB-rated generic versions of Otsuka’s Samsca (tolvaptan) 30 mg tablets.

What is tolvaptan 15mg?

Generic Name: tolvaptan This medication is used to treat low levels of salt (sodium) in the blood, which can result from conditions such as heart failure and certain hormone imbalances. Tolvaptan belongs to a class of drugs known as vasopressin receptor antagonists.

Is tolvaptan available?

Tolvaptan is also available as brand 15 mg tablets (Samsca) and brand 15 mg and 30 mg tablets (Jynarque®). Samsca carries a boxed warning to initiate and re-initiate in a hospital and monitor serum sodium; and not for use for autosomal dominant polycystic kidney disease.

When do you give tolvaptan?

Tolvaptan (Samsca) comes as a tablet to take by mouth. It is usually taken once a day with or without food for no longer than 30 days. At the beginning of your treatment, you will be given tolvaptan (Samsca) at a regularly scheduled time in the hospital.

  • August 18, 2022