What is the meaning of Desmoplasia?

What is the meaning of Desmoplasia?

(DES-moh-PLAS-tik) Causing or forming adhesions or fibrous connective tissue within a tumor.

What is stromal Desmoplasia?

Desmoplasia is the result of increased synthesis of extracellular matrix proteins and collagen by stromal cells. It is considered to be a reaction and response of the host tissue against invasive cancer cells.[5]

What is the meaning of desmoplastic reaction?

In medicine, desmoplasia is the growth of fibrous or connective tissue. It is also called desmoplastic reaction to emphasize that it is secondary to an insult. Desmoplasia may occur around a neoplasm, causing dense fibrosis around the tumor, or scar tissue (adhesions) within the abdomen after abdominal surgery.

What are anaplastic cells?

Listen to pronunciation. (A-nuh-PLAS-tik) A term used to describe cancer cells that divide rapidly and have little or no resemblance to normal cells.

What is desmoplasia of breast?

A desmoplastic reaction is a host response, characterized by a fibrotic connective tissue. It classically occurs due to the presence of malignant cells, and was initially described in breast cancer. Histologically desmoplasia may involve very few cells or an abundance of them.

What is desmoplasia in pathology?

Desmoplasia (derived from Greek words desmos, meaning “connective,” and plasia, meaning “formation”) is a term for the formation of connective tissue in response to tumors. From: Pathology Secrets (Third Edition), 2009.

What is anaplasia example?

Examples of Anaplasia Anaplasia gives cancers a very unpredictable nature, making them hard to treat with chemotherapy and radiation. This can be seen in the two cancers Leiomyosarcoma (a malignant smooth muscle tumor) and Leiomyoma (a benign smooth muscle tumor).

What does no atypia mean?

(ay-TIH-pee-uh) State of being not typical or normal. In medicine, atypia is an abnormality in cells in tissue.

What is signet ring cell?

In histology, a signet ring cell is a cell with a large vacuole. The malignant type is seen predominantly in carcinomas.

Are benign cells anaplastic?

In some adenomas (benign glandular tumors), a change can cause the cells to become less differentiated, or to show anaplasia. In this case, these benign cells can actually become a malignant adenocarcinoma. Most often, they do not.

What is differentiation and anaplasia?

Anaplasia is a qualitative alteration of differentiation. Anaplastic cells are typically poorly differentiated or undifferentiated and exhibit advanced cellular pleomorphism. In fact, anaplasia and pleomorphism are sometimes used incorrectly as synonyms. Pleomorphism refers to variation in the size and shape of cells.