What is the difference between Prevnar 13 and Synflorix?
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What is the difference between Prevnar 13 and Synflorix?
» All age groups, including young infants, respond well to this type of vaccine. » Synflorix includes 10 pneumococcal bacteria types, and can indirectly protect against two additional types. » Prevenar 13 includes the same pneumococcal types as Synflorix, plus three additional types.
What type of vaccine is Synflorix?
Pneumococcal polysaccharide and non-typeable H. influenzae protein D conjugate vaccine, 10-valent adsorbed.
Is Synflorix a conjugate vaccine?
SYNFLORIX™ is a 10-valent pneumococcal conjugate vaccine (PCV-10) (containing serotypes 1, 4, 5, 6B, 7F, 9V, 14, 18C, 19F, 23F) which has had Marketing Authorisation (MA) in Europe since 2009.
What is the indication of pneumococcal vaccine?
Pneumococcal vaccination is indicated for adults with risk factors for pneumococcal disease or for severe adverse outcomes should disease occur. Pneumococcal vaccination is also a routine part of infant and childhood immunization schedules worldwide.
When is synflorix given?
Synflorix® will be administered on the routine National Immunisation Schedule as a primary course at 6 weeks and 5 months of age followed by a booster dose at 12 months of age.
Which is better PCV10 vs PCV13?
The sample size provided 98% power for an overall conclusion on the difference between two doses of PCV10 and PCV13, and more than 99% power for an overall conclusion on the non-inferiority of two doses of PCV13 compared with three doses of PCV10.
When is Synflorix given?
Does Synflorix vaccine cause fever?
The most common side effects with Synflorix (which may affect more than 1 in 10 people) are pain, redness and swelling at the injection site, fever, drowsiness, irritability and loss of appetite. The majority of these reactions were of mild to moderate severity and were not long lasting.
How long is Synflorix effective?
A booster dose is recommended at least 6 months after the last primary dose (see section 5.1 Pharmacodynamic properties).
How do you inject Synflorix?
It is usually given as an injection into the muscle (intramuscular) of the upper arm or upper thigh. It is usually given twice or thrice with at least a gap of 1 month between each dose. Inform your doctor if your child has an infection with a high temperature, as vaccination may need to be delayed until recovery.
Does Synflorix cause fever?
Although most of these side effects listed below don’t happen very often, they could lead to serious problems if you do not check with your child’s doctor or seek medical attention. Check with your child’s doctor as soon as possible if any of the following side effects occur: fever over 39°C (102.2°F)
What vaccine is PCV10?
The PCV-10 vaccine protects against infection by the pneumococcus bacteria, one of the most common causes of pneumonia in children. It also protects against some other infections caused by the pneumococcus, such as some forms of meningitis and bacteremia.
What is PCV10?
PCV10, 10-valent pneumococcal conjugate vaccine. Protects against pneumococcal disease caused by at least 10 types of Streptococcus pneumoniae.
When do you give Synflorix vaccine?
When is pneumonia vaccine recommended?
If you’re 65 or over, you should be offered a type of pneumococcal vaccine known as the pneumococcal polysaccharide vaccine (PPV). This one-off vaccination is very effective at protecting you against serious forms of pneumococcal infection.
Which is best pneumonia vaccine?
CDC recommends pneumococcal vaccination for young children, older adults, and certain other people. All children younger than 2 years old should receive PCV13. Children 2 through 18 years old with certain medical conditions should receive PCV13 and PPSV23.
Which one is better PCV10 or PCV13?
Conclusion. Both PCV10 and PCV13 were immunogenic and induced a booster response. Compared to the PCV10 group, the PCV13 group showed higher levels for serotype 19F GMCs and avidity, pre- as well as post-booster, although opsonophagocytosis did not differ significantly between groups.
