What is injection perflutren lipid microspheres?

What is injection perflutren lipid microspheres?

Perflutren lipid microsphere injection is used during an echocardiogram to help diagnose or find problems in the heart. Perflutren lipid microsphere is an ultrasound contrast agent. Ultrasound contrast agents are used to help provide a clear picture during ultrasound.

What type of drug is perflutren?

Perflutren is an ultrasound contrast agent that is used to improve the quality of an echocardiogram (ultrasound of the heart).

How is perflutren administered?

The maximum dose is either two bolus doses or one single intravenous infusion. The recommended bolus dose for activated DEFINITY® is 10 microliters (microL)/kg of the activated product by intravenous bolus injection within 30 60 seconds, followed by a 10 mL saline flush.

What is DEFINITY injection?

DEFINITY® is an injectable cardiovascular ultrasound enhancement agent comprised of lipid-coated echogenic microbubbles filled with octafluoropropane gas. Administration of DEFINITY® enhances clinicians’ view of the left ventricle of the heart during an echocardiogram to aid with diagnosis.

Why sodium chloride injection is given?

Sodium chloride 23.4% injection is used to replenish lost water and salt in your body due to certain conditions (eg, hyponatremia or low salt syndrome). It is also used as an additive for total parenteral nutrition (TPN) and carbohydrate-containing IV fluids.

Is DEFINITY safe?

No deaths or serious adverse reactions were reported, suggesting that these reactions are unlikely to occur at a rate of more than 0.3% when DEFINITY is used according to recommendations. The following adverse reactions have been identified during the post-marketing use of perflutren-containing microsphere products.

What is the most common reaction to DEFINITY?

Common side effects of Definity include:

• sore throat,
• runny or stuffy nose,
• shortness of breath,
• itching,
• rash,
• hives,
• increased sweating, and.
• dry skin.

Is sodium chloride safe for pregnancy?

Sodium Chloride should be used during pregnancy only if the possible benefit outweighs the possible risk to the unborn baby. No studies have been done in animals, and no well-controlled studies have been done in pregnant women. Sodium Chloride should be given to a pregnant woman only if clearly needed.

What happens if sodium chloride is injected?

Infusion of excess sodium chloride 0.9% solution may cause fluid overload or electrolyte imbalance. Intravenous administration of solutions may cause local reactions including pain, vein irritation and thrombophlebitis. Extravasation of solution may cause tissue injury.

Why would someone use a sodium chloride injection?

Descriptions. Sodium chloride 23.4% injection is used to replenish lost water and salt in your body due to certain conditions (eg, hyponatremia or low salt syndrome). It is also used as an additive for total parenteral nutrition (TPN) and carbohydrate-containing IV fluids.

How long does sodium chloride injection last?

Unfortunately, they are being stored for extended periods of time without any knowledge of the effects that extended cooling or heating may have on their stability or sterility. The manufacturer recommends that these fluids be discarded after 28 days.