What is basement membrane dystrophy?

What is basement membrane dystrophy?

Epithelial basement membrane dystrophy (EBMD) is a disease that affects the anterior cornea, causing characteristic slit lamp findings which may result in decreased vision and/or recurrent corneal erosions.

What is the treatment for epithelial basement membrane dystrophy?

You can do a simple epithelial debridement, where you just scrape off all of the loose epithelium. This usually works well. Sometimes, a microscopic irregular basement membrane is left underneath the epithelium, and if you want to remove that, you can use a diamond burr polisher.

What is the treatment for anterior basement membrane dystrophy?

Typically these erosions can heal themselves within a day or two. The first line of treatment for ABMD typically involves the use of lubricating tears or ointment. Reoccurring or symptomatic erosions may involve the use of bandage contact lenses, antibiotic ointments, or topical/oral steroids.

Are Abmd and EBMD the same?

Epithelial Basement Membrane Dystrophy (EBMD), is the most common of the corneal dystrophies. Ii is also known as Map-Dot-Fingerprint Dystrophy and Anterior Basement Membrane Dystrophy (ABMD), . Since it was first described by Cogan et.al. in 1964, it is also known as Cogan’s Microcystic Corneal Dystrophy.

How common is epithelial basement membrane dystrophy?

Epithelial basement membrane dystrophy (EBMD) is the most common type of corneal dystrophy, affecting 2% of the population.

Is epithelial basement membrane dystrophy rare?

Epithelial basement membrane dystrophy is a common form of corneal dystrophy and is also known as map-dot-fingerprint dystrophy and Cogan microcystic dystrophy. This extremely rare form of corneal dystrophy affects the epithelial layer of the cornea.

Is epithelial basement membrane dystrophy hereditary?

EBMD usually is not inherited, occurring randomly in people with no family history of EBMD. However, familial cases with autosomal dominant inheritance have been reported. In some people with EBMD, a genetic change in the TGFBI gene has been identified as the cause.

What is the best treatment for endothelial dystrophy?

Posterior lamellar surgery (also referred to as endothelial keratoplasty) is now the standard of care in treatment of early to moderate Fuchs’ endothelial dystrophy. The most common type of DSEK performed in the US is sometimes referred to as Descemet’s Stripping Automated Endothelial Keratoplasty (DSAEK).

How does corneal dystrophy affect the body?

Corneal dystrophies are characterized by the accumulation of foreign material in one or more of the five layers of the cornea. Such material may cause the cornea to lose its transparency potentially causing loss of vision or blurred vision.

  • July 25, 2022