What are bt474 cells?

What are bt474 cells?

BT-474 is a cell line exhibiting epithelial morphology that was isolated from a solid, invasive ductal carcinoma of the breast obtained from a 60-year-old, White, female breast cancer patient. Use these cells in your cancer research.

What are skbr3 cells?

SK-BR-3 is a human breast cancer cell line that overexpresses the Her2 (Neu/ErbB-2) gene product. These cells display an epithelial morphology in tissue culture and are capable of forming poorly differentiated tumors in immunocompromised mice.

What are t47d cells?

T-47D are epithelial cells isolated from a pleural effusion obtained from a 54-year-old female patient with an infiltrating ductal carcinoma of the breast. Use these cells in your breast cancer research.

What does MDA-MB-231 mean?

Abbreviation / Long Form : MDA-MB 231 / M.D. Anderson – Metastatic Breast 231. [Related PubMed/MEDLINE]

Does MCF 7 express HER2?

Discoveries in breast cancer pathology through experiments using MCF-7 cells. MCF-7 sub-lines demonstrate a wide divergence in the relative expression of ER, PR and HER2.

What does SkBr3 stand for?

SkBr3 (also known as SK-BR-3) is a human breast cancer cell line isolated by the Memorial Sloan–Kettering Cancer Center in 1970 that is used in therapeutic research, especially in context of HER2 targeting.

What does T-47D stand for?

T47D stands for Human Breast Cancer Cells.

What is the doubling time for MDA-MB-231?

about 38h
Hi Nairrita, the doubling time of MDA-MB-231 cells is about 38h according to ATCC. I usually start with the density of 7,500 cells/cm2 in 96-well plate for 3 days MTS assay.

What is trastuzumab used for?

Herceptin is the brand name of a medicine called trastuzumab. It’s used to treat some types of breast cancer, oesophageal cancer and stomach cancer.

Are MCF-7 cells metastatic?

MCF-7 is a poorly-aggressive and non-invasive cell line (9), normally being considered to have low metastatic potential (8).

Are MCF-7 cells invasive?

Though MCF7 is categorized as poorly invasive, its migration in the 2D surface is found to be comparable to the highly invasive MDA MB 231 in the current study.

What is MCF 10A?

MCF 10A is an epithelial cell line that was isolated in 1984 from the mammary gland of a White, 36-year-old female with fibrocystic breasts. This cell line was deposited by the Michigan Cancer Foundation. Homo sapiens, human. Cell type epithelial cell Morphology epithelial Tissue Breast; Mammary gland Disease.

What is MDA MB 468 cell line?

MDA-MB-468 is a cell line with epithelial morphology that was isolated from a pleural effusion of a 51-year-old Black female patient with metastatic adenocarcinoma of the breast. These cells have applications in breast cancer and immuno-oncology research.

Is MCF7 triple-negative?

MCF7 and MDA-MB-231 cells represent a striking example in that they are both invasive ductal/breast carcinoma cells, yet they have many phenotypic/genotypic differences: MCF7 are hormone dependent (both estrogen and progesterone receptor positive—ER and PR), while MDA-MB-231 are triple negative.

  • September 24, 2022