What medications could cause blood clots?

What medications could cause blood clots?

24, 2014 (HealthDay News) — People who use painkillers called nonsteroidal anti-inflammatory drugs (NSAIDs) — which include aspirin, naproxen (Aleve) and ibuprofen (Advil, Motrin) — may be at increased risk for potentially deadly blood clots, a new study suggests.

What medications increase risk of pulmonary embolism?

Certain medications (eg, birth control pills, hormone replacement therapy, tamoxifen, thalidomide, erythropoietin, cancer chemotherapy medications). The risk of a blood clot is further increased in people who use one of these medications and also have other risk factors.

What increases risk of thromboembolism?

Risk factors convincingly demonstrated for VTE include increasing age, prolonged immobility, malignancy, major surgery, multiple trauma, prior VTE, and chronic heart failure (Table 2).

Can antibiotics cause thrombosis?

For antibiotics used mainly for infections of the skin the risk of venous thrombosis was about 4-fold (IRR 4·1; 95% CI, 1·7–10·0) increased, with roughly similar risks for DVT and PE.

How do NSAIDs cause blood clots?

NSAIDs work by blocking a specific group of enzymes called cyclo-oxygenase enzymes (COX enzymes). These enzymes are involved in the production of prostaglandins which control many different processes such as inflammation, blood flow, and the formation of blood clots.

Can certain drugs cause pulmonary embolism?

Talc or hydrous magnesium silicate used to cut drugs for illicit injectable drug use lead to foreign-body pulmonary embolism, pulmonary granulomatosis, progressive massive fibrosis, and pulmonary hypertension. Frequent symptoms include cough, dyspnea, and hemoptysis.

Can drugs cause blood clots in the lungs?

Certain medications may increase the risk of developing blood clots in the lungs. These include certain types of hormonal birth control such as Yaz (drospirenone) or NuvaRing, estrogen replacement therapy, testosterone replacement therapy or Xeljanz (tofacitinib).

Which antibiotics cause blood clots?

Some antibiotics, such as rifampin, decrease warfarin’s ability to “thin” the blood, increasing the risk a blood clot will form.

Does Tramadol affect blood clotting?

Tramadol seems to impair hemostasis and increasing the bleeding tendency by affecting the activity of coagulation factors rather than platelets and fibrinogen levels, as MCF values did not show a statistically significant difference recorded in the present study.

Why do COX 2 inhibitors cause thrombosis?

COX-2 inhibition without COX-1 inhibition will therefore preserve the synthesis of the vasoconstrictive thromboxane A2 and inhibit production of the vasodilator prostacyclin, tipping the balance toward vasoconstriction and thrombosis.

What medicines cause pulmonary edema?

Additional drugs that can cause noncardiogenic pulmonary edema include carbamazepine, cytarabine, erythromycin, hydrochlorothiazide, IV radiographic contrast agents, methotrexate, protamine, tamoxifen, and tumor necrosis factor.

What is drug induced pulmonary disease?

Definition. Drug-induced pulmonary disease is lung disease brought on by a bad reaction to a medicine. Pulmonary means related to the lungs.

Which drugs cause pulmonary edema?

Many drugs — ranging from aspirin to illegal drugs such as heroin and cocaine — are known to cause pulmonary edema. Blood clot in the lungs (pulmonary embolism). A blood clot moving from the blood vessels in the legs to the lungs can cause pulmonary edema.

Can NSAIDs cause blood clots?

While aspirin prevents blood platelets from clumping together to form dangerous clots in blood vessels, non-aspirin NSAIDs can increase blood clot formation, which can lead to heart attacks and strokes.

  • October 1, 2022