What is a spirocyclic compound?
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What is a spirocyclic compound?
A spiro compound, or spirane, from the Latin spīra, meaning a twist or coil, is a chemical compound, typically an organic compound, that presents a twisted structure of two or more rings (a ring system), in which 2 or 3 rings are linked together by one common atom, examples of which are shown at right.
Are spiro compounds chiral?
The spiro compounds can also exhibit chirality due to the presence of central chirality. When both, the central chirality and the axial chirality appear in the same molecule, the configurational descriptor has to be assigned based on central chirality.
How do you synthesize spiro compounds?
A one-pot route for the synthesis of spiro-isobenzofuran compounds was developed via the condensation reaction of ninhydrin with 4-amino-1,2-naphthoquinones or 2-amino-1,4-naphthoquinones in acetic acid followed by the oxidative cleavage of the corresponding vicinal diols at room temperature.
What is aliphatic heterocyclic compounds?
Aliphatic Heterocyclic compounds are those cyclic heterocycles that do not contain any double bond. The properties of aliphatic heterocyclic compounds are mainly affected due to ring strain. Examples of aliphatic heterocyclic compounds are Aziridine, Oxirane, Thiirane, etc.
Is Naphthalene a bicyclic compound?
Naphthalene is a bicyclic aromatic hydrocarbon derived from coal tar or crude oil. It is an insecticide that is also used as a repellent.
What is fused ring system?
FR-1.2 Fused ring system. A system where each bond is part of a ring; where each ring is ortho-fused (FR-1.1. 1), or ortho- and peri-fused (FR-1.1. 2), to at least one other ring; and where no bond is common to more than two rings is termed a fused ring system.
Can a spiro compound be aromatic?
Introduction. Spiro polycyclic aromatic compounds consist of two π-conjugated systems that are perpendicularly fixed by an sp3-hybridized spiro atom. They have been widely studied and used as organic functional materials, because of their unique properties.
What is fused bicyclic?
In fused/condensed bicyclic compounds, two rings share two adjacent atoms. In other words, the rings share one covalent bond, i.e. the so-called bridgehead atoms are directly connected (e.g. α-thujene and decalin).
Which heterocyclic compound is not aromatic?
Tetrahydrofuran is a heterocyclic compound. But it is not an aromatic compound. Although it contains a lone pair of electrons, these electrons are not delocalized as there is no conjugated system.
Is naphthalene is non benzenoid aromatic compound?
Examples of benzenoid aromatic compounds include naphthalene, anthracene, phenanthrene, aniline etc. A non benzenoid aromatic compound contains conjugated pi electron systems with a ring of 5 to 7 carbon atoms.
What is the aromaticity of naphthalene?
Naphthalene, with two fused rings, is the simplest polycyclic aromatic molecule. Note that all the carbon atoms except those at the points of fusion have a bond to a hydrogen atom. Naphthalene, which has 10 π electrons, satisfies the Hückel rule for aromaticity.
Which is fused cyclic aromatic compounds?
biphenyl. Answer: Option C. Workspace. Report Errors. Kindly mention the details of the error here… [
What is fused heterocyclic?
• Fused heterocycles are systems constructed by. combining two or more rings. • The rings are fused if they are linked in such a way that. each ring has one common bond (fusion bond) to each. other.
How do you know if a compound is aromatic?
Four Criteria for Aromaticity
- The molecule is cyclic (a ring of atoms)
- The molecule is planar (all atoms in the molecule lie in the same plane)
- The molecule is fully conjugated (p orbitals at every atom in the ring)
- The molecule has 4n+2 π electrons (n=0 or any positive integer)
Which one is not an aromatic compound?
1,3,5− heptatriene is not an aromatic compound because complete delocalization of pi electrons is not possible in it and it is not planar.
Are bicyclic compounds aromatic?
In 2017 experimental evidence was reported for bicycloaromaticity (dual aromaticity) to exist in a bicyclic porphyrinoid. This system has been described as aromatic with two ring systems of 26 (n=6) and 34 (n=8) electrons.
Which of the following heterocycles is bicyclic?
A bicyclic compound can be carbocyclic (all of the ring atoms are carbons), or heterocyclic (the rings atoms consist of at least two elements), like DABCO.
