What causes Hallermann Streiff?

What causes Hallermann Streiff?

In almost all reported cases, Hallermann-Streiff syndrome has occurred randomly for unknown reasons (sporadically), most likely due to a new spontaneous dominant genetic change (mutation). There have been reports of patients with this disorder reproducing successfully and bearing multiple normal children.

Does Hallermann Streiff syndrome affect intelligence?

The syndrome can be associated with sleep apnea. The physical characteristics of the syndrome can result in difficult intubation by medical professionals. Intelligence is usually normal.

What is hellerman syndrome?

HSS is a rare disease. It is characterized by bird-like face, dental abnormalities, hypotrichosis, atrophy of skin, proportionate nanism, congenital cataracts and bilateral microphthalmia[1]. HSS was initially noted in 1983, however the description was not complete.

How common is Hallermann Streiff syndrome?

Hallermann-Streiff syndrome (oculomandibulodyscephaly syndrome) is rare, with approximately 150 cases reported.

What syndrome causes close set eyes?

Overview. Noonan syndrome is a genetic disorder that prevents normal development in various parts of the body. A person can be affected by Noonan syndrome in a wide variety of ways. These include unusual facial characteristics, short stature, heart defects, other physical problems and possible developmental delays.

What is the life expectancy of someone with Jacob’s syndrome?

Results. The average prevalence was 14.2 47,XYY persons per 100,000, which is reduced compared to the expected 98 per 100,000. Their median age at diagnosis was 17.1 years. We found a significantly decreased lifespan from 77.9 years (controls) to 67.5 years (47,XYY persons).

How do you get Jacobsen syndrome?

Jacobsen syndrome is caused by a loss of genetic material in chromosome 11. This occurs as an entirely random error in cell division in most cases. This normally occurs during the formation of reproductive cells or early on during fetal development.