What are the benefits of indole-3-carbinol?

What are the benefits of indole-3-carbinol?

There is interest in indole-3-carbinol for cancer prevention, particularly breast, cervical, and colon cancer, because diets with higher amounts of fruits and vegetables are linked to a decreased risk of these cancers. Indole-3-carbinol is present in several vegetables and might help protect against cancer.

Does DIM have side effects?

Current human research doesn’t show DIM supplements to be toxic or have serious side effects. The most common side effects include darkening of the urine, an increase in bowel movements, headaches, and gas ( 3 , 8 ). Less common side effects include nausea, vomiting, diarrhea, and skin rash ( 3 ).

What is carbinol used for?

Indole-3-carbinol is used for prevention of breast cancer, colon cancer, and other types of cancer. The National Institutes of Health (NIH) has reviewed indole-3-carbinol as a possible cancer preventive agent and is now sponsoring clinical research for breast cancer prevention.

Can DIM cause liver damage?

DIM appears to alter liver function in such a manner that an increased amount of estrogen becomes metabolized into inactive forms. In addition, DIN blocks certain effects of estrogen on cells; however, it may enhance other effects of estrogen.

Is indole-3-carbinol good for men?

In conclusion, Indole-3-carbinol is useful for both men and women.

Does I3C lower estrogen?

Results: In both men and women, I3C significantly increased the urinary excretion of C-2 estrogens. The urinary concentrations of nearly all other estrogen metabolites, including levels of estradiol, estrone, estriol, and 16alpha-hydroxyestrone, were lower after I3C treatment.

Can indole-3-carbinol help lose weight?

These findings suggest that I3C has a potential benefit in preventing obesity and metabolic disorders, and the action for I3C in vivo may involve multiple mechanisms including decreased adipogenesis and inflammation, along with activated thermogenesis.

Is DIM OK to take long term?

DIM has been taken as a dietary supplement for many years without any reports of adverse effects, and DIM’s safety has been evaluated. The use of DIM in an animal study at hundreds of times the amount provided in dietary supplements produced no adverse effects.

Can DIM hurt your liver?

Is DIM good for your liver?

They have also shown that DIM enhances the activity of enzymes found in certain pathways in the liver. These enzymes contribute to the healthy metabolism of estrogen that reduces the risk of cancer development.

Is DIM hard on the liver?

DIM decreases liver infiltration of MNCs and decreases macrophage activation in the infiltrating MNCs.

Does DIM affect thyroid?

Diindolylmethane (DIM), a dietary supplement, found naturally in cruciferous vegetables (such as cabbage, cauliflower, broccoli, & Brussels sprouts) has been studied extensively in recent years for its anti-cancer effects….DIM as a Treatment for Thyroid Disease.

Last Update Posted: May 3, 2013
Last Verified: April 2013

What is the synonym of isobutylmethylcarbinol?

Synonyms & Trade Names. Isobutylmethylcarbinol, Methyl amyl alcohol, 4-Methyl-2-pentanol, MIBC. CAS No. 108-11-2. RTECS No.

What are the side effects of methocarbamol?

Common methocarbamol side effects may include: 1 headache, dizziness, drowsiness; 2 fever; 3 confusion, problems with memory; 4 nausea, vomiting, upset stomach; 5 blurred vision, double vision; 6 flushing (warmth, redness, or tingly feeling); 7 sleep problems ( insomnia ); or 8 lack of coordination.

How do you take methocarbamol?

Methocarbamol oral is taken by mouth. You may need to reduce your dose after the first 2 or 3 days of treatment. Carefully follow your doctor’s dosing instructions. Methocarbamol injection is injected into a muscle or given as an infusion into a vein.

  • October 9, 2022