How does XTANDI treat prostate cancer?

How does XTANDI treat prostate cancer?

Enzalutamide is among several hormone therapies that have been developed to prevent the androgen-fueled growth of castrate-resistant prostate cancers. This drug works by keeping androgens from binding to the androgen receptors on prostate cancer cells.

Who is the manufacturer of XTANDI?

XTANDI® (enzalutamide) Approved by U.S. FDA for the Treatment of Metastatic Castration-Sensitive Prostate Cancer | Pfizer.

What is XTANDI prescribed for?

XTANDI is a prescription medicine used to treat men with prostate cancer that no longer responds to a hormone therapy or surgical treatment to lower testosterone OR has spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosterone.

Is XTANDI a hormone therapy?

Enzalutamide (Xtandi®) is a type of hormone therapy for men with prostate cancer that has spread to other parts of the body (advanced prostate cancer).

How long can you live taking Xtandi?

Treatment with Xtandi resulted in a median overall survival time of 18.4 months (95% CI 17.3 to not yet reached) compared with 13.6 months (95% CI 11.3 to 15.8) in the placebo recipients (p<0.001).

Is Xtandi available in Canada?

MARKHAM, ON, June 16, 2020 /CNW/ – Astellas Pharma Canada, Inc., announced that Health Canada, following a Priority Review, has approved XTANDI® (enzalutamide) for the treatment of patients with metastatic castration-sensitive prostate cancer (mCSPC).

How can I get Xtandi for free?

For people who are uninsured. The Astellas Patient Assistance Program provides XTANDI at no cost to patients who meet the program eligibility requirements. All patients in this program who qualify receive their XTANDI prescription at no cost. Call 1-855-8XTANDI (1-855-898-2634) to see if you qualify.

How long does Xtandi extend life?

How long does Xtandi extend life? In the AFFIRM trial, treatment with Xtandi extended life by almost 5 months. Treatment with Xtandi resulted in a median overall survival time of 18.4 months (95% CI 17.3 to not yet reached) compared with 13.6 months (95% CI 11.3 to 15.8) in the placebo recipients (p<0.001).

How much is Xtandi a month?

Xtandi Coupon & Prices – Cost $49 per month.

How long can you live taking xtandi?

How much is xtandi a month?

When Xtandi stops working What is next?

If your doctor thinks Xtandi has stopped working they will advise you to stop taking it. In about 50 percent of the men whose PSA level starts to rise again while on antiandrogen therapy, stopping treatment will lead to antiandrogen withdrawal syndrome or antiandrogen withdrawal response (AAWR).

How much does enzalutamide cost in Canada?

OR: Page 6 pCODR Final Economic Guidance Report – Enzalutamide (Xtandi) for non-Metastatic Castration-Resistant Prostate Cancer pERC Meeting: February 21, 2019; Early Conversion: March 26, 2019 © 2019 pCODR | PAN-CANADIAN ONCOLOGY DRUG REVIEW 2 One 7.5 mg subcutaneous depot injection every month: Daily cost: $13.85 28- …

How do I pay for Xtandi?

Helping eligible patients find ways to pay for XTANDI. Call XTANDI Support Solutions® at 1-855-8XTANDI (1-855-898-2634) to speak with a dedicated access specialist who can help you find out what options exist for eligible patients to pay for XTANDI. We’re available Monday through Friday, 8 AM to 8 PM ET.

What is the success rate of Xtandi?

By Year 4, the Xtandi group showed a 70.6% overall survival rate compared with just 57% for placebo. The study showed Xtandi, used alongside the AD therapy, slashed the risk of death by 34% compared with the AD therapy alone.

How long can you stay on Xtandi?

Xtandi is typically taken until prostate cancer starts to progress or spread (metastasize), or until the patient can no longer tolerate therapy because of the side effects or adverse events it causes.

Does Xtandi lower PSA?

Official answer. A decrease in prostate-specific antigen (PSA) levels is seen in some men with advanced prostate cancer who are treated with Xtandi (enzalutamide).

Can you get Xtandi in Canada?

  • August 23, 2022