How do you Nebulize amphotericin B?

How do you Nebulize amphotericin B?

Amphotericin B (am-fo-ter-i-sin) is an antifungal medicine….How to Nebulize

  1. Inject the 0.5 mL syringe contents into the nebulizer reservoir.
  2. Pour Sterile Water for Inhalation 2.5 mL (1/2 packet) into the medicine reservoir of the nebulizer.
  3. Put the nebulizer together and start the treatment.

How do you give amphotericin B emulsion?

The recommended daily dosage for adults and children is 5 mg/kg given as a single infusion, administered intravenously at a rate of about 2.5 mg/kg/hour.

Can you use bottled water in nebulizer?

Do not use water from the faucet, bottled, or distilled water. You can make water sterile by boiling it for 5 minutes. Use this water once, and then throw it out. Place the nebulizer pieces on a paper towel to dry.

How do you administer amphotericin infusion?

How should this medicine be used? Amphotericin B injection comes as a solid powder cake to be made into a solution and then injected intravenously (into a vein) by a nurse or a doctor. Amphotericin B injection is usually infused (injected slowly) intravenously over a period of 2 to 6 hours once daily.

What is the difference between liposomal amphotericin B and amphotericin B?

Liposomal amphotericin B provides an equally efficacious alternative to conventional amphotericin B deoxycholate in patients with AIDS and acute cryptococcal meningitis. Liposomal amphotericin B at a dosage of 3 mg/kg/day is accompanied by significantly fewer adverse effects.

How fast does amphotericin B work?

Chronic anaemia is common after several weeks of amphotericin B in addition to a general feeling of ill health and loss of appetite. It usually takes 2-4 weeks for these symptoms to recover following a course of amphotericin B.

When administering amphotericin B IV what particular precaution should you need to consider?

EXERCISE CAUTION to prevent inadvertent FUNGIZONE (amphotericin b) Intravenous overdose, which can result in potentially fatal cardiac or cardiorespiratory arrest. Verify the product name and dosage if dose prescribed exceeds 1.5 mg/kg (see OVERDOSAGE and DOSAGE AND ADMINISTRATION).

What are the side effects of amphotericin B?

More common

  • Fever and chills.
  • headache.
  • increased or decreased urination.
  • irregular heartbeat.
  • muscle cramps or pain.
  • nausea.
  • pain at the place of injection.
  • unusual tiredness or weakness.

What is the advantage of liposomal amphotericin B?

Liposomal amphotericin B appears to be an effective alternative to conventional amphotericin B in the management of immunocompromised patients with proven or suspected fungal infections. Use of the drug is facilitated by its greatly improved tolerability profile compared with conventional amphotericin B.

  • July 28, 2022