How do you give Penicillin G Potassium?

How do you give Penicillin G Potassium?

Buffered Pfizerpen (penicillin g potassium) for Injection may be given intramuscularly or by continuous intravenous drip for dosages of 500,000, 1,000,000, or 5,000,000 units. It is also suitable for intrapleural, intraarticular, and other local instillations.

Can penicillin G be administered IV?

Penicillin G benzathine and penicillin G procaine injection should never be given intravenously (into a vein), because this may cause serious or life-threatening side effects or death.

What is the most appropriate way to administer penicillin G?

Penicillin G procaine (aqueous) is for intramuscular injection only. Administer by DEEP INTRAMUSCULAR INJECTION in the upper, outer quadrant of the buttock (dorsogluteal) or the ventrogluteal site. In neonates, infants and small children, the midlateral aspect of the thigh may be preferable.

What is Penicillin G Potassium used for?

Penicillin G injection is used to treat and prevent certain infections caused by bacteria. Penicillin G injection is in a class of medications called penicillins. It works by killing bacteria that cause infections.

Why is penicillin G given iv?

Penicillin G is produced by fermentation of Penicillium chrysogenum. Because of its poor oral bioavailability, it is generally given intravenously as a sodium, potassium, benzathine, or procaine salt.

How do you dilute penicillin G?

Loosen powder in the vial; hold horizontally and rotate while slowly directing diluent against vial wall. Shake vigorously after diluent added. Refrigerate reconstituted vials if not used immediately; unstable in solution at room temperature.

How do you administer IV penicillin?

For injection dosage form:

  1. Adults, teenagers, and children weighing more than 40 kg (88 pounds)—250 mg to 1 gram injected into a vein or muscle every four to six hours.
  2. Children weighing up to 40 kg (88 pounds)—Dose is based on body weight and must be determined by your doctor.

What bacteria does penicillin G treat?

An antibiotic that works against a wide range of bacteria, Penicillin G is effective against infections caused by some forms of Streptococcus pyogenes, Streptococcus pneumoniae, Staphylcoccus, Clostridium bacteria, and many others.

What do you reconstitute penicillin G with?

Penicillin G Potassium or Sodium For IM injection, reconstitute vials containing 1 or 5 million penicillin G units (as penicillin G potassium) or vials containing 5 million penicillin G units (as penicillin G sodium) to desired concentration using amount of diluent specified by the manufacturer.

How is penicillin G benzathine administered?

Long-acting penicillin G benzathine (Bicillin® L-A) is the preferred antibiotic treatment for syphilis. Each dose requires two intramuscular injections, one injection into each hip or buttock muscle at the same visit. One dose of Bicillin® L-A 2.4 million units is usually adequate to treat early syphilis.

What is an IV piggyback?

The term “piggyback” is used because the smaller bag is plugged into, or “takes a piggyback ride” on, the established main IV line. The smaller bag is removed once the medication has been infused; the main IV remains unchanged. This “piggyback” technique means the patient does not require multiple IV sites.

Is penicillin G the same as penicillin?

Penicillin G and penicillin V (phenoxymethylpenicillin) are “natural” penicillins, with a narrow-spectrum of activity due to the development of penicillinases (β-lactamases active against penicillins). Staphylococci, initially sensitive to penicillin G, are now considered highly resistant.

What are the side effects of penicillin G?

Common side effects of penicillin G potassium include:

  • injection site reactions (pain, redness, swelling, bruising, or irritation),
  • twitching or muscle spasm,
  • overactive reflexes,
  • mild skin rash,
  • nausea,
  • vomiting,
  • upset stomach,
  • diarrhea,

How do you administer benzylpenicillin IM?

High doses should be administered by intravenous injection or infusion, with intravenous doses in excess of 1.2g (2 mega units) being given slowly, taking at least one minute for each 300 mg (0.5 mega unit) to avoid high levels causing irritation of the central nervous system and/or electrolyte imbalance.

How do you prepare penicillin G injection?

Draw up 1 mL (150 mg of penicillin) of solution and add 4 mL of water for injection to make a final volume of 5mL with a concentration of 30 mg/mL solution. Add 1.6 mL water for injection to the 600 mg vial to make a 300 mg/mL solution. Administration IV infusion over 15−30 minutes.

What is the difference between IV and IVPB?

A secondary IV, also know as IV Piggyback, and abbreviated IVPB, is a second IV medication or fluid that is hung alongside the first and which is attached to the first set of IV tubing through one of the injection ports that is below the drip chamber of the primary IV (if we were to connect it through the injection …

Does penicillin G make you sleepy?

Common side effects of penicillin G benzathine may include: feeling anxious, nervous, weak, or tired; headache, dizziness, drowsiness; muscle or joint pain; or.

  • July 30, 2022